With the recent deployment of commercial 5G systems, the technology evolution is moving towards more autonomous, self-configuring, intelligent networks and devices to support the new forthcoming data- and process-hungry applications of the next generation of the communication system. AI is considered a good fit for complicated non-convex optimization problems that are lacking optimal analytical solutions, and computation-intensive problems that are too costly to solve in real-time. Research works have provided promising results in applying AI in different use cases, ranging from physical- to application-layers, from edge- to core network-services and applications. Taking also into consideration the advances in big data computing technology, AI applied to the wireless domain has the potential to reshape the design and deployment of wireless networks and enable the formation of a self-adaptive, more power-aware, smart, and resilient communication ecosystem. In the proposed panel, we will explore and discuss the potentials and challenges of leveraging AI for the next generation of communication networks. Devices’ Role for AI-native 6G Networks, AI-driven Communication and Computation Co-design: the EU 6G Flagship Project Hexa-X Perspective AI-enabled Intelligent RAN Optimization AI/ML in 5G Evolution Toward 6G Strategic Standardisation for AI & Communications