Connected and autonomous vehicles and related technologies are expected to profoundly transform future intelligent transportation systems (ITS). These technologies are ushering in an era of smart transportation that can end traffic accidents, improve public transportation, and drastically reduce congestion and carbon emissions. Connected and smart vehicles will bring massive amounts of data that will need to be transmitted over 5G and beyond networks as part of the broader framework of future smart cities. The stringent demands of autonomous vehicles and data-intensive applications in ITS are already driving new requirements for future communication systems. Fueled by the amounts of data available, autonomous vehicles and intelligent transportation systems will increasingly rely on artificial intelligence to improve efficiency and performance. A variety of artificial intelligence techniques are being developed to bolster dynamic decision making, system cybersecurity and intelligent traffic control. Artificial intelligence is expected to be one of the key enablers of smart autonomous transportation supported by future communication networks. In this Industry forum, we will bring together experts from industry and the public sector who are driving and leading efforts in the autonomous vehicles and ITS arena, to discuss challenges and future directions in the area with the ICC 2021 audience.